Background: Abuse of different drugs is rising globally. It has been seen that the younger future generations of the society are the most impacted. With drug abuse comes various systemic and local complications. One such complication is the worsening periodontal condition. The present study was conducted with the aim to evaluate the complications and effect of different drugs on periodontal health. Materials and methods: The present study was conducted amongst 120 subjects who were divided into three groups. Group I included heavy drug addicts, group II included low drug addicts and group III were controls. Periodontal condition was evaluated amongst all the subjects and recorded in a tabulated form. The results were evaluated using SPSS software. Results: The mean age of the patients was 37.54±56 years. There was significant difference in the oral conditions and symptoms amongst the addicts and controls. Bleeding on probing, clinical attachment loss and gingival index also varied significantly between the groups. Conclusion: From the present study it was concluded that the periodontal condition is significantly affected in drug addicts with worse among the heroin addicts. Clinical significance: It is well known fact that psychoactive substance abuse leads to reduction in immune response, poor oral hygiene leading to precarious oral environment as well as dry mouth. Dentist being a part of community health services, it is imperative to assess periodontal conditions of drug addicts as well as take part in campaigning and educating these subjects about deleterious effects of drugs and their impact on body as well as oral cavity. Keyword: Addicts; Drug, Periodontal